Flavonoids and its related phenolic compounds have found to have antioxidant, anti-inflammatory, anti cancer, weight loss, circulation management and hepatoprotective properties but owing to their polar nature they have poor absorption which ultimately lead to their poor systemic bioavailability, thereby their therapeutic efficacy gets reduced. Phytosome – a phytolipid delivery system can surpass these drawbacks .phytosomes are phospholipid-substrate complex in which there occurs the formation of weak hydrogen bonds between the polar portion while the non polar tail of phospholipid wraps over the complex thereby imparting lipophilic character to it and hence increases its absorption. Phytosomes differs from liposomes to greater extent. The commercial production of phytosomes is easy. Characterization techniques are available which makes them to readily usable drug delivery system.
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